·临床医学系统研究·
SYSTEMS MEDICINE 系统医学系统医学2018年5月第3卷第9期
DOI:10.19368/jki.2096-1782.2018.09.021文拉法辛及黛力新老年患者焦虑抑郁障碍的
效果比较分析
王小云
云南省楚雄州人民医院精神心理科，云南楚雄675000
[摘要]目的比较文拉法辛及黛力新老年患者焦虑抑郁障碍的效果。方法选取2016年6月—2017年7月该院收治的80例焦虑抑郁障碍老年患者作为研究对象，随机将患者分成两组，一组采用文拉法辛进行，为观察组，一组采用黛力新进行，为参照组，对比两组患者的近期和远期疗效。结果观察组患者2周后HAMA 评分为(15.2±1.4)分,HAMD 评分为(15.4±2.2)分，参照组患者2周后HAMA 评分为(15.4±1.5)分,HAMD 评分为(15.3±2.3)分，两组患者HAMA 与HAMD 评分比较差异无统计学意义(P >0.05)；观察组患者6个月后上述两项评分分别为(10.4±1.6)分、(11.8±0.2)分，参照组患者后6个月后上述两项评分分别为(14.2±2.4)分、(14.9±2.4)分，两组患者各项评分比较差异有统计学意义(P <0.05)；观察组患者不良反应发生率为7.5%(3例)，参照组患者不良反应发生率为10.0%
(4例)，两组患者不良反应发生率比较差异无统计学意义(P >0.05)。结论文拉法辛及黛力新老年患者焦虑抑郁障碍在安全性以及近期疗效上来看并无明显差异，但从长期疗效上来看，文拉法辛的效果更好，可在临床中进行推广。
[关键词]文拉法辛；黛力新；老年患者；焦虑抑郁障碍
[中图分类号]R749[文献标识码]A [文章编号]2096-1782(2018)05(a)-0021-03
Comparison and Analysis of the Efficacy of Venlafaxine and Deanxin in Treating Elderly Patients with Anxiety and Depression
WANG Xiao-yun
reference group
Department of Psychology,People's Hospital of Chuxiong Prefecture,Chuxiong,Yunnan Province,675000China [Abstract]Objective This paper tries to compare the efficacy of venlafaxine and Deanxin in the treatment of anxiety and depression in elderly patients.Methods 80elderly patients with anxiety and depression treated in this hospital from June 2016to July 2017were randomly selected and divided into two groups.One group was treated with venlafaxine as the observation group.Deanxin was treated as a reference group to compare the short -term and long -te
rm efficacy of the two groups of patients.Results In the observation group,the HAMA score was (15.2±1.4)points,the HAMD score was (15.4±2.2)points after 2weeks of treatment,the HAMA score was (15.4±1.5)points,and the HAMD score was (15.3±2.3)points after 2weeks of treatment in the reference group.The scores of HAMA and HAMD were not statistically significant in the two groups (P >0.05);the two scores in the observation group were (10.4±1.6)points and (11.8±0.2)points after 6months of treatment.In the reference group,the above two scores were (14.2±2.4)points and (14.9±2.4)points six months after the treatment.The scores of the two groups were statistically significant (P <0.05);the observation group patients of the incidence of
adverse reactions was 7.5%(3cases).The incidence of adverse reactions in the reference group was 10.0%(4cas⁃es).The incidence of adverse reactions in the two groups was not statistically significant (P >0.05).Conclusion Both venlafaxine and Delixin have no significant difference in the safety and short -term efficacy of elderly pa⁃
tients with anxiety and depression.However,in terms of long-term efficacy,venlafaxine is more effective and can
be promoted in clinical practice.[Key words]Venlafaxine;Relixin;Elderly patients;Anxiety and depression
[作者简介]王小云(1974-)，女，云南大姚人，本科，主治医
师，主要从事精神心理科临床工作。
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