2016年版WHO淋巴造血组织肿瘤分类
WHO淋巴造血组织肿瘤分类（2016年版）
骨髓增殖性肿瘤  Myeloproliferative neoplasm（MPN）
慢性髓系白血病，BCR-ABL1 阳性
Chronic myeloid leukemia, BCR-ABL1–positive（CML, BCR-ABL1 ）
慢性中性粒细胞白血病
Chronic neutrophilic leukaemia（CNL）
真性红细胞增多症
Polycythemia vera（PV）
原发性骨髓纤维化
Primary myelofibrosis(PMF)
原发性骨髓纤维化，纤维化前/早期
Primary myelofibrosis，prefibrotic/early stage
原发性骨髓纤维化，明显纤维化期
Primary myelofibrosis，overt fibrotic stage
原发性血小板增多症
Essential thrombocythaemia（ET）
慢性嗜酸粒细胞白血病，非特指
Chronic eosinophilic leukaemia, not otherwise specified (CEL, NOS)
骨髓增生性肿瘤，不能分类
Myeloproliferative neoplasm, unclassifiable (MPN,U)
肥大细胞增多症  Mastocytosis
皮肤肥大细胞增多症
Cutaneous mastocytosis(CM)
系统性肥大细胞增多症
Systemic mastocytosis(SM)
肥大细胞白血病
Mast cell leukaemia（MCL）
肥大细胞肉瘤
Mast cell sarcoma (MCS)
皮肤外肥大细胞瘤
Extracutaneous mastocytoma
髓系或淋系肿瘤伴嗜酸性粒细胞增多伴PDGFRA、PDGFRB或FGFR1基因异常，或伴PCM1-JAK2
Myloid lymphoid neoplasams with esonophilia and abnormalities of PDGFRA, PDGFRB ,or FGFRI, or withPCM1-JAK2
髓系/淋系肿瘤伴PDGFRA重排
Myeloid/lymphoid neoplasms with PDGFRA rearrangement
髓系/淋系肿瘤伴PDGFRB重排
Myeloid/lymphoid neoplasms with PDGFRB rearrangement
髓系/淋巴细胞系肿瘤伴FGFR1重排
Myeloid/lymphoid neoplasms with FGFR1 rearrangemen
暂定类型：髓系/淋巴肿瘤伴PCM1-JAK2
Provisional entity: Myeloid/lymphoid neoplasms with PCM1-JAK2
骨髓增生异常/骨髓增殖性肿瘤  Myelodysplastic/myeloproliferative neoplasms (MDS/MPN)
慢性粒-单核细胞白血病
Chronic myelomonocytic leukaemia (CMML)
不典型慢性髓系白血病，BCR-ABL1阴性
Atypical chronic myeloid leukaemia.BCR-ABL1-negative (aCML)
幼年性粒单核细胞白血病
Juvenile myelomonocytic leukaemia (JMML)
骨髓增生异常/骨髓增殖性肿瘤伴环形铁粒幼细胞和血小板增多
Myelodysplastic/myeloproliferative neoplasm with ring sideroblasts and thrombocytosis (
MDS/MPN-RS-T)
骨髓增生异常/骨髓增生性肿瘤，不能分类
Myelodysplastic/myeloproliferative neoplasm,unclassifiable (MDS/MPN，U)
骨髓增生异常综合征  Myelodysplastic syndrome (MDS)
骨髓增生异常综合征伴单系异型增生
Myelodysplastic syndrome with single lineage dysplasia (MDS-SLD)
骨髓增生异常综合征伴环形铁粒幼细胞
Myelodysplastic syndrome with ring sideroblasts (MDS-RS)
骨髓增生异常综合征伴环形铁粒幼细胞及单系异型增生
Myelodysplastic syndrome with ring sideroblasts and single lineage dysplasia(MDS-RS-SLD)
骨髓增生异常综合征伴环形铁粒幼细胞及多系异型增生
Myelodysplastic syndrome with ring sideroblasts and multilineage dysplasia(MDS-RS-MLD)
骨髓增生异常综合征伴多系异型增生
Myelodysplastic syndrome with multilineage dysplasia(MDS-MLD)
骨髓增生异常综合征伴原始细胞增多
Myelodysplastic syndrome with excess blasts (MDS-EB,MDS-EB1/MDS-EB2)
骨髓增生异常综合征伴孤立性5q-
Myelodysplastic syndrome associated with isolated del(MDS,5q-)
骨髓增生异常综合征，不能分类
Myelodysplastic syndrome, unclassifiable (MDS-U)
暂定类型：幼年性难治性血细胞减少
Provisional entity：Refractory cytopenia ofchildhood
髓系肿瘤伴先天易感性  Myeloid neoplasms with germline predisposition
急性髓系白血病及相关肿瘤  Acute myeloid leukemia (AML)and related neoplasms
急性髓系白血病伴重现性遗传学异常  AML with recurrent genetic abnormalities
急性髓系白血病伴t(8;21)(q22;q22.1)；RUNX1-RUNX1T1
AML with t(8 ;21)(q22;q22);RUNXI-RUNX1Tl
急性髓系白血病伴inv(16)(p13.1;1q22) 或t(16;16) (p13.1; q22)；CBFB-MYH11
AML with inv(16)(p13.1;1q22 )or t(16;16)(p13.1;q22); CBFB-MYHl1
急性早幼粒细胞白血病伴PML-RARA
Acute promyelocytic leukaemia with PML-RARA
急性髓系白血病伴t(9;11)(p21.3;q23.3)；MLLT3-KMT2A
AML with t(9;11)(p21.3;q23.3); MLLT3-KMT2A
急性髓系白血病伴t(6;9)(p23;q34.1)；DEK-NUP214
AML with 1(6;9)(p23;q34.1 ); DEK-NUP214
急性髓系白血病伴inv(3)(q21.3;q26.2) 或 t(3;3)(q21.3;q26.2)；GATA2,MECOM
AML with inv(3)(q21.3;q26.2) 或 t(3;3)(q21.3;q26.2)；GATA2,MECOM
急性髓系白血病（原巨核细胞性）伴t(1;22)(p13.3;q13.3)；RBM15-MKL1
AML (megakaryoblastic) with t(1;22)(p 13.3;q13.3); RBMI5-MKLI
暂定类型：急性髓系白血病伴BCR-ABL1
Provisional entity: AML with BCR-ABL1
急性髓系白血病伴NPM1突变
AML with mutated NPM1
急性髓系白血病伴CEBPA双等位基因突变
AML with biallelic mutations ofCEBPA
暂定类型：急性髓系白血病伴RUNX1突变
Provisional entity: AML with mutatedRUNX1
急性髓系白血病伴骨髓增生异常相关改变  AML with myelodysplasia-related changes
相关髓系肿瘤  Therapy-related myeloid neoplasms
急性髓系白血病，非特指型  Acute myeloid leukaemia，NOS (AML,NOS)
急性髓系白血病伴微小分化
AML with minimal differentiation
急性髓系白血病不伴成熟
proliferation
AML without maturation
急性髓系白血病伴成熟
AML with maturation
急性粒-单核细胞白血病
Acute myelomonocytic leukaemia
急性原单和单核细胞白血病
Acute monoblastic and monocytic leukaemia
纯红白血病
Pure erythroid leukemia
急性原巨核细胞白血病
Acute megakaryoblastic leukaemia
急性嗜碱性粒细胞白血病
Acute basophilic leukaemia

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