专利名称：DIFFERENTIATION OF ISOBARIC AMINO ACIDS AND OTHER SPECIES
发明人：HEATH, James R.,LEE, Su Seong,LIM,
Jaehong,CHA, Junhoe,TAN, Sylvia,YEO, Shi
Yun
申请号：SG2009/000258
申请日：20090722reaction between pvp and amino
公开号：WO2011/010964A1
公开日：
20110127
专利内容由知识产权出版社提供
专利附图：
摘要：Techniques for differentiating isobaric species are described. An isobaric species
may be substituted with a tagging species identified using mass spectrometry. The isobaric species may be a subunit of a first polymer having a defined sequence, e.g., the isobaric species may be an amino acid in a protein or a peptide sequence. A tagging species may be substituted for the isobaric species in a second polymer having an otherwise identical sequence as the first polymer. The second polymer may have the same number of sequences as the first polymer, and substantially the same sequence of subunits, with a few exceptions such as the tagging species for the isobaric species. The first polymer and the second polymer may be prepared in the same reaction vessel. A polymer/protein of defined subunit sequence containing an isobaric species or a tagging species may be analyzed by mass spectrometry to determine the sequence.
申请人：AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH,HEATH, James R.,LEE, Su Seong,LIM, Jaehong,CHA, Junhoe,TAN, Sylvia,YEO, Shi Yun
地址：1 Fusionopolis Way #20-10, Connexis Singapore 138632 SG,c/o Institute of Bioengineering and Nanotechnology, 31 Biopolis Way, The Nanos, #04-01 Singapore 138669 SG,c/o Institute of Bioengine
ering and Nanotechnology, 31 Biopolis Way, The Nanos, #04-01 Singapore 138669 SG,c/o Institute of Bioengineering and Nanotechnology, 31 Biopolis Way, The Nanos, #04-01 Singapore 138669 SG,c/o Institute of Bioengineering and Nanotechnology, 31 Biopolis Way, The Nanos, #04-01 Singapore 138669 SG,c/o Institute of Bioengineering and Nanotechnology, 31 Biopolis Way, The Nanos, #04-01 Singapore 138669 SG,c/o Institute of Bioengineering and Nanotechnology, 31 Biopolis Way, The Nanos, #04-01 Singapore 138669 SG
国籍：SG,SG,SG,SG,SG,SG,SG
代理人：YU SARN AUDREY & PARTNERS
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