专利名称：BIOACTIVE SUBSTANCE-BLOOD PROTEIN CONJUGATE AND STABILIZATION OF A
BIOACTIVE SUBSTANCE USING THE SAME 发明人：PARK, Jong-Il,SOUNG, Min-Gyu,KIM, Heung-Jae,LIM, Chae-Jin,KANG, Jong-Phil,CHOI, Ho-
Il
申请号：KR2006004427
申请日：20061027
公开号：WO07/049940P1
公开日：
20070503
专利内容由知识产权出版社提供
摘要：This invention relates to a technology of modifying low-molecular-weight bioactive substances with short in vivo half-life and low stability in order to achieve a stable and efficient in vivo delivery thereof. More specifically, the present invention relates to a stable bioactive substance-blood protein conjugate, wherein a low-molecular- weight bioactive substance is ex vivo conjugated with a specific functional group on a blood protein through a reactive group, the low-molecular-weight bioactive substance is available as a drug for treatment and prevention in mammals including human and selected from the group consisting of a natural substance; and a method of a stable and efficient in vivo delivery of the low-molecular-weight bioactive substance based on the use of the bioactive substance-blood protein conjugate.
申请人：PARK, Jong-Il,SOUNG, Min-Gyu,KIM, Heung-Jae,LIM, Chae-Jin,KANG, Jong-Phil,CHOI, Ho-Il
地址：385-19 Doryong-dong, Yuseong-gu Daejeon, 305-340 KR,108-206, Sejong apt.
Jeonmin-dong, Yoosung-gu Daejeon, 305-390 KR,110-1003 Hyundai apt. Eumnae-dong, Daedeok-gu Daejeon, 306-761 KR,102-508, Hansol Apt Songgang-dong, Yoosung-gu Deajeon 305-803 KR,102-102, Mokryun Apt. Sangdae-dong, Yuseong-gu Daejeon 305-313 KR,401, 305-4 Jeonmin-dong, Yuseong-gu Daejeon, 305-390 KR,108-901, Hanwool apt. Sinsung-dong, Yoosung-gu Deajeon, 305-345 KR
国籍：KR,KR,KR,KR,KR,KR,KR
reactive substance代理机构：YOU ME PATENT & LAW FIRM
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