专利名称:STRUCTURAL CAROTENOID ANALOGS FOR THE INHIBITION AND AMELIORATION OF
DISEASE
发明人:LOCKWOOD, Samuel, Fournier,O'MALLEY, Sean,WATUMULL, David, G.,HIX, Laura,
M.,JACKSON, Henry,NADOLSKI, Geoff
申请号:EP03772051.3
申请日:20030729
公开号:EP1532108A2
公开日:
20050525
专利内容由知识产权出版社提供
摘要:A method for inhibiting and/or ameliorating the occurrence of diseases associated with reactive oxygen species, reactive nitrogen species, radicals and/or non-radicals in a subject whereby a subject is administered a carotenoid structural analog, either alone or in combination with another carotenoid analog, or co-antioxidant formulation. The analog or analog combination is administered such that the subject's risk of experiencing diseases associated with reactive oxygen species, reactive nitrogen species, radicals and/or non-radicals may be thereby reduced. The analog or analog combination may be administered to a subject for the inhibition and/or amelioration of ischemia-reperfusion injury. The analog or analog combination may be administered to a subject for the inhibition and/or amelioration of liver disease. The analog or analog combination may be administered to a subject for the inhibition and/or amelioration of cancer. The analog or analog combination may be administered to a subject for the inhibition and/or amelioration of cardiac arrhythmia and/or sudden cardiac death. The
reactive oxygen species是什么意思analog or analog combination may be administered to a subject for the inhibition and/or amelioration of
any disease that involves production of reactive oxygen species, reactive nitrogen species, radicals and/or non-radicals. In one embodiment, a water-soluble
and/or water-dispersible astaxanthin analog is particularly effective. This invention further includes pharmaceutical compositions comprising structural carotenoid analogs either alone or in combination.
申请人:Hawaii Biotech, Inc.
地址:Suite 236,99-193 Aiea Heights Drive Aiea, HI 96701 US
国籍:US
代理机构:Casalonga, Axel
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