专利名称：Random transposon insertion in
staphylococcus aureus and use thereof to
identify essential genes
发明人：KIM FOLGER BRUCE,KEVIN HOU,PAUL
WARRENER,JENNIFER MCLARNAN
申请号：AU2003278714
申请日：20030820
arduino字符串转数组公开号：AU2003278714A8
公开日：
20040311
专利内容由知识产权出版社提供
摘要：The invention provides a method for generating a database of candidate essential genes in Staphylococcus aureus, as well as otherwise important genes that, when mutated, lead to a growth attenuated phenotype. Such genes and mutants of such genes are important for identifying antibacterial agents suitable for treating and preventing S. aureus infections. The invention includes methods for confirming the essentiality or importance of candidate genes, as well as methods for utilizing those genes to screen for new antibacterial drugs. The invention also includes the antibacterial agents identified using the disclosed methods, as well as methods of using the same for treating and preventing Staphylococcus infection.
申请人：CHIRON CORPORATION
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