专利名称：CO-STIMULATORY MOLECULES
发明人：PUNNONEN, Juha,LAZETIC, Alexandra, L., L.,LEONG, Steven, R.,CHANG, Chia-Chun,
Jean,APT, Doris,GUSTAFSSON, Claes
申请号：EP01952193.9
申请日：20010622
公开号：EP1360290A2
公开日：
doris
20031112
专利内容由知识产权出版社提供
摘要：The invention provides polynucleotides and polypeptides encoded therefrom having advantageous properties, including an ability of the polypeptides to preferentially bind a CD28 or CTLA-4 receptor at a level greater or less than the ability of human B7-1 to bind CD28 or CTLA-4, or to induce or inhibit altered level of T cell proliferation response greater compared to that generated by human B7-1. The polypeptides and polynucleotides of the invention are useful in therapeutic and prophylactic treatment methods, gene therapy applications, and vaccines.
申请人：Maxygen, Inc.
地址：515, Galveston Drive Redwood City, CA 94063 US
国籍：US
代理机构：Kjerrumgaard, Lars Bo
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