专利名称:Capillary mixer with adjustable reaction
chamber volume for mass spectrometry
发明人:Lars Konermann,Derek J. Wilson
申请号:US10788843
申请日:20040227
公开号:US06870154B1
公开日:
20050322
专利内容由知识产权出版社提供
专利附图:
摘要:Disclosed is a capillary mixer for mixing first and second reactant solutions to form a mixed solution prior to delivering the mixed solution to an ion source of a mass spectrometer. The mixer com
prises: a pair of concentric capillaries consisting of: an outer
capillary connected at a distal end to an inlet of the ion source and being connected at a proximal end to a source of the second reactant solution; and an inner capillary within the outer capillary, thereby forming an annular intercapillary space between the outer and inner capillaries, wherein: the inner capillary is connected at a proximal end to a source of the first reactant solution and has an opening at or near a distal end, is slidably sealed to the outer capillary at or near the proximal end of the outer capillary and is movable back and forth within the outer capillary, whereby the first reactant solution is delivered through the inner capillary and the second solution is delivered through the intercapillary space; and the first and second reactant solutions get mixed to form the mixed solution in a mixing region within the intercapillary space into which the first reactant solution is expelled through the opening. Because the inner capillary is movable, the reaction chamber volume is adjustable. As a result, both spectral and kinetic modes of operation can be conducted by using the same mixer.
申请人:Lars Konermann,Derek J. Wilson
地址:London CA,London CA
国籍:CA,CA
reaction mass
代理机构:Baker & Daniels
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