专利名称：NOVEL ANTIBACTERIAL AMIDE COMPOUND 发明人：TEODOORU HAABAATO
HASUKERU,TOOMASU FUREDORITSUKU
MITSUKU,JIYOSEFU PIITAA
SANTSUE,DEIITORITSUHI SHIYUBUAISUreactive carbonyl species
申请号：JP3147680
申请日：19800311
公开号：JPS55147291A
公开日：
19801117
专利内容由知识产权出版社提供
摘要：Novel organic amide compounds which are N- 2- (acylaminoacylamino or aminoacylamino)phenyl!-4-hydroxy-5- pyrimidinylcarbonyl!cephalosporin compounds having broad spectrum antibacterial utility are provided by (a) reacting the free amino acid of the appropriate cephalosporin or the acid salt or silylated derivative or complex thereof with a reactive derivative of the corresponding N-2- (acylaminoacylamino or aminoacylamino)phenyl!-4-hydroxy-5-pyrimidine carboxylic acid or (b) reacting the free amino acid 7- aminocephalosporanic acid or a related compound or the acid salt or silylated derivative thereof with a reactive derivative of the corresponding D-N- 2-(acylaminoacylamino or aminoacylamino)phenyl!-4- hydroxy-5-pyrimidinylcarbonyl!-2-substituted glycine. Pharmaceutical compositions containing said compounds and methods for treating infections using said compositions are also disclosed.
申请人：WARNER LAMBERT CO
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