雷贝拉唑联合曲美布汀功能性消化不良的疗效观察
目的 观察雷贝拉唑联合曲美布汀功能性消化不良临床疗效。方法 200例功能性消化不良患者随机分为两组，分别为观察组88例，对照组112例。两组患者均每日早餐前服用1次雷贝拉唑肠溶胶囊，20mg/次；观察组患者每日三餐后加服曲美布汀，0.1g/次，疗程2w。结果 观察组上腹痛、上腹灼烧感、餐后饱胀症状改善情况明显优于对照组（P＜0.01）；嗳气症状改善情况无统计学意义（P>0.05）。对照组总有效率为74.1%；观察组总有效率为79.5%。两组均未出现明显不良反应。结论 雷贝拉唑与曲美布汀联用可明显改善功能性消化不良的症状，且较为安全。
Abstract：Objective To observe the curative effect of combined therapy of rabeprazole and trimebutin for functional dyspepsia. Methods 200 patients with functional dyspepsia were randomly grouped into observation group（n=88）and controls group （n=112）.The patients in the two groups were given rabeprazole sodium enteric-coated capsules 20mg 1 times a day before breakfast for 2 weeks ， The patients in the observation group were given trimebutin 0.1g 3 times a day after meals in addition to rabeprazole for 2 weeks.Resul
trimets The symptoms of upper abdominal pain， stomach burn ， abdominal distention after meals in the patients in the observation group were more improved than in the control group（P 0.05），见表1。对照组总有效率为74.1%；观察组总有效率为79.5%，两组差异无统计学意义（P>0.05），见表2。

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